Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X‐ray photoelectron spectroscopy approach
Identifieur interne : 009A04 ( Main/Exploration ); précédent : 009A03; suivant : 009A05Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X‐ray photoelectron spectroscopy approach
Auteurs : A. Arys [Belgique] ; C. Philippart [Belgique] ; N. Dourov [Belgique] ; Y. He [Belgique] ; Q. T. Le [Belgique] ; J. J. Pireaux [Belgique]Source :
- Journal of Biomedical Materials Research [ 0021-9304 ] ; 1998-09.
Descripteurs français
- Wicri :
- topic : Recherche médicale, Oxyde, Titane.
English descriptors
- KwdEn :
- Arys, Astm, Atomic percent, Atomic percent concentrations, Auger electron spectroscopic studies, Belgian fund, Binding energy, Biological tissues, Body tissues, Branemark, Bulk composition, Carbon material, Cell metabolism, Chemical composition, Complex geometry, Connective tissue, Corrosion resistance, Cpti, Cpti implants, Critical threshold, Crystallographic structure, Dent, Dental implants, Different brands, Different mechanisms, Electron microprobe, Electron microprobe analysis, Electron microprobe measurements, Element traces, Elemental composition, Favor osseointegration, Fifth world biomater, Foreign elements, Granular bodies, Hati, Hematoxylin eosin stain, High surface sensitivity, Histological, Histological slides, Implant, Implant failure, Implant surface, Implant threads, Integration failure, Iron particles, Jbma, John wiley sons, Large amount, Light microscopy, Medical research, Metal ions, Methods section, Microprobe, Nitride, Nitride species, Nitrogen content, Nobel pharma, Osseointegration, Osseointegration failure, Osteoid tissue, Other hand, Other implants, Overlayer, Oxide, Oxide dissolution, Oxide thickness, Oxidoreduction mechanism, Oxygen signal, Partial dissolution, Photoelectron, Photoelectron spectroscopy, Photoelectron spectroscopy results, Potential difference, Proprietary preparation procedures, Protective titanium dioxide overlayer, Pure titanium, Reactive metal, Reference implants, Sample surface, Sterile package, Surface analysis, Surface properties, Surface roughness, Surface science aspects, Surgical procedure, Thin tio2, Tio2, Tio2 layer, Tio2 overlayer, Titanium, Titanium implant surfaces, Titanium implants, Titanium layer, Titanium metal, Wide scan, Zinc salts.
- Teeft :
- Arys, Astm, Atomic percent, Atomic percent concentrations, Auger electron spectroscopic studies, Belgian fund, Binding energy, Biological tissues, Body tissues, Branemark, Bulk composition, Carbon material, Cell metabolism, Chemical composition, Complex geometry, Connective tissue, Corrosion resistance, Cpti, Cpti implants, Critical threshold, Crystallographic structure, Dent, Dental implants, Different brands, Different mechanisms, Electron microprobe, Electron microprobe analysis, Electron microprobe measurements, Element traces, Elemental composition, Favor osseointegration, Fifth world biomater, Foreign elements, Granular bodies, Hati, Hematoxylin eosin stain, High surface sensitivity, Histological, Histological slides, Implant, Implant failure, Implant surface, Implant threads, Integration failure, Iron particles, Jbma, John wiley sons, Large amount, Light microscopy, Medical research, Metal ions, Methods section, Microprobe, Nitride, Nitride species, Nitrogen content, Nobel pharma, Osseointegration, Osseointegration failure, Osteoid tissue, Other hand, Other implants, Overlayer, Oxide, Oxide dissolution, Oxide thickness, Oxidoreduction mechanism, Oxygen signal, Partial dissolution, Photoelectron, Photoelectron spectroscopy, Photoelectron spectroscopy results, Potential difference, Proprietary preparation procedures, Protective titanium dioxide overlayer, Pure titanium, Reactive metal, Reference implants, Sample surface, Sterile package, Surface analysis, Surface properties, Surface roughness, Surface science aspects, Surgical procedure, Thin tio2, Tio2, Tio2 layer, Tio2 overlayer, Titanium, Titanium implant surfaces, Titanium implants, Titanium layer, Titanium metal, Wide scan, Zinc salts.
Abstract
A multitechnique approach has been used to characterize the surface of nonosseointegrated titanium implants and the surrounding biological tissues. Five pure titanium dental implants were used as reference, and 25 removed implants were studied. Surface and in‐depth chemical compositions of the implants (from a total of 16 patients) were investigated by X‐ray photoelectron spectroscopy (XPS). Histological slides of the surrounding tissues were examined by light microscopy, XPS, and electron microprobe analysis. None of the failed implants presented the regular surface composition and depth profile of the TiO2 overlayer; foreign elements (Ca, Na, P, Si, Cl, Zn, Pb, and Al) were observed on some implants. Fibrosis, lymphocytic and plasmocytic infiltrates, and granulomatous lesions were detected in the surrounding tissues. XPS and electron microprobe analysis indicated the presence of Zn, Fe, Sn, and Ti in the tissues. As a possible scenario for implant failure, we propose and discuss a oxidoreduction mechanism, leading to a partial dissolution or the complete dissociation of the protective titanium dioxide overlayer and to ion diffusion through the surrounding tissues. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 43: 300–312, 1998
Url:
DOI: 10.1002/(SICI)1097-4636(199823)43:3<300::AID-JBM11>3.0.CO;2-J
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000020
- to stream Istex, to step Curation: 000020
- to stream Istex, to step Checkpoint: 004667
- to stream Main, to step Merge: 009E74
- to stream Main, to step Curation: 009A04
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X‐ray photoelectron spectroscopy approach</title><author><name sortKey="Arys, A" sort="Arys, A" uniqKey="Arys A" first="A." last="Arys">A. Arys</name></author><author><name sortKey="Philippart, C" sort="Philippart, C" uniqKey="Philippart C" first="C." last="Philippart">C. Philippart</name></author><author><name sortKey="Dourov, N" sort="Dourov, N" uniqKey="Dourov N" first="N." last="Dourov">N. Dourov</name></author><author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name></author><author><name sortKey="Le, Q T" sort="Le, Q T" uniqKey="Le Q" first="Q. T." last="Le">Q. T. Le</name></author><author><name sortKey="Pireaux, J J" sort="Pireaux, J J" uniqKey="Pireaux J" first="J. J." last="Pireaux">J. J. Pireaux</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0048047ED90777A2254776581E303F523FC57BD1</idno><date when="1998" year="1998">1998</date><idno type="doi">10.1002/(SICI)1097-4636(199823)43:3<300::AID-JBM11>3.0.CO;2-J</idno><idno type="url">https://api.istex.fr/document/0048047ED90777A2254776581E303F523FC57BD1/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000020</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000020</idno><idno type="wicri:Area/Istex/Curation">000020</idno><idno type="wicri:Area/Istex/Checkpoint">004667</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">004667</idno><idno type="wicri:doubleKey">0021-9304:1998:Arys A:analysis:of:titanium</idno><idno type="wicri:Area/Main/Merge">009E74</idno><idno type="wicri:Area/Main/Curation">009A04</idno><idno type="wicri:Area/Main/Exploration">009A04</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X‐ray photoelectron spectroscopy approach</title><author><name sortKey="Arys, A" sort="Arys, A" uniqKey="Arys A" first="A." last="Arys">A. Arys</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>Université Libre de Bruxelles, Laboratoire d'Anatomie Pathologique et de Microscopie Electronique, Faculté de Médecine‐Erasme (Bat. C), Route de Lennick 808, B‐1070 Brussels</wicri:regionArea><orgName type="university">Université libre de Bruxelles</orgName><placeName><settlement type="city">Bruxelles</settlement><region type="region" nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Philippart, C" sort="Philippart, C" uniqKey="Philippart C" first="C." last="Philippart">C. Philippart</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>Université Libre de Bruxelles, Laboratoire d'Anatomie Pathologique et de Microscopie Electronique, Faculté de Médecine‐Erasme (Bat. C), Route de Lennick 808, B‐1070 Brussels</wicri:regionArea><orgName type="university">Université libre de Bruxelles</orgName><placeName><settlement type="city">Bruxelles</settlement><region type="region" nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Dourov, N" sort="Dourov, N" uniqKey="Dourov N" first="N." last="Dourov">N. Dourov</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>Université Libre de Bruxelles, Laboratoire d'Anatomie Pathologique et de Microscopie Electronique, Faculté de Médecine‐Erasme (Bat. C), Route de Lennick 808, B‐1070 Brussels</wicri:regionArea><orgName type="university">Université libre de Bruxelles</orgName><placeName><settlement type="city">Bruxelles</settlement><region type="region" nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Correspondence address: Université Libre de Bruxelles, Laboratoire d'Anatomie Pathologique et de Microscopie Electronique, Faculté de Médecine‐Erasme (Bat. C), Route de Lennick 808, B‐1070 Brussels</wicri:regionArea><wicri:noRegion>B‐1070 Brussels</wicri:noRegion></affiliation></author><author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Facultés Universitaires N‐D de la Paix, Laboratoire LISE, B‐5000 Namur</wicri:regionArea><wicri:noRegion>B‐5000 Namur</wicri:noRegion></affiliation></author><author><name sortKey="Le, Q T" sort="Le, Q T" uniqKey="Le Q" first="Q. T." last="Le">Q. T. Le</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Facultés Universitaires N‐D de la Paix, Laboratoire LISE, B‐5000 Namur</wicri:regionArea><wicri:noRegion>B‐5000 Namur</wicri:noRegion></affiliation></author><author><name sortKey="Pireaux, J J" sort="Pireaux, J J" uniqKey="Pireaux J" first="J. J." last="Pireaux">J. J. Pireaux</name><affiliation wicri:level="1"><country xml:lang="fr">Belgique</country><wicri:regionArea>Facultés Universitaires N‐D de la Paix, Laboratoire LISE, B‐5000 Namur</wicri:regionArea><wicri:noRegion>B‐5000 Namur</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Biomedical Materials Research</title><title level="j" type="alt">JOURNAL OF BIOMEDICAL MATERIALS RESEARCH</title><idno type="ISSN">0021-9304</idno><idno type="eISSN">1097-4636</idno><imprint><biblScope unit="vol">43</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="300">300</biblScope><biblScope unit="page" to="312">312</biblScope><biblScope unit="page-count">13</biblScope><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="1998-09">1998-09</date></imprint><idno type="ISSN">0021-9304</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0021-9304</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arys</term><term>Astm</term><term>Atomic percent</term><term>Atomic percent concentrations</term><term>Auger electron spectroscopic studies</term><term>Belgian fund</term><term>Binding energy</term><term>Biological tissues</term><term>Body tissues</term><term>Branemark</term><term>Bulk composition</term><term>Carbon material</term><term>Cell metabolism</term><term>Chemical composition</term><term>Complex geometry</term><term>Connective tissue</term><term>Corrosion resistance</term><term>Cpti</term><term>Cpti implants</term><term>Critical threshold</term><term>Crystallographic structure</term><term>Dent</term><term>Dental implants</term><term>Different brands</term><term>Different mechanisms</term><term>Electron microprobe</term><term>Electron microprobe analysis</term><term>Electron microprobe measurements</term><term>Element traces</term><term>Elemental composition</term><term>Favor osseointegration</term><term>Fifth world biomater</term><term>Foreign elements</term><term>Granular bodies</term><term>Hati</term><term>Hematoxylin eosin stain</term><term>High surface sensitivity</term><term>Histological</term><term>Histological slides</term><term>Implant</term><term>Implant failure</term><term>Implant surface</term><term>Implant threads</term><term>Integration failure</term><term>Iron particles</term><term>Jbma</term><term>John wiley sons</term><term>Large amount</term><term>Light microscopy</term><term>Medical research</term><term>Metal ions</term><term>Methods section</term><term>Microprobe</term><term>Nitride</term><term>Nitride species</term><term>Nitrogen content</term><term>Nobel pharma</term><term>Osseointegration</term><term>Osseointegration failure</term><term>Osteoid tissue</term><term>Other hand</term><term>Other implants</term><term>Overlayer</term><term>Oxide</term><term>Oxide dissolution</term><term>Oxide thickness</term><term>Oxidoreduction mechanism</term><term>Oxygen signal</term><term>Partial dissolution</term><term>Photoelectron</term><term>Photoelectron spectroscopy</term><term>Photoelectron spectroscopy results</term><term>Potential difference</term><term>Proprietary preparation procedures</term><term>Protective titanium dioxide overlayer</term><term>Pure titanium</term><term>Reactive metal</term><term>Reference implants</term><term>Sample surface</term><term>Sterile package</term><term>Surface analysis</term><term>Surface properties</term><term>Surface roughness</term><term>Surface science aspects</term><term>Surgical procedure</term><term>Thin tio2</term><term>Tio2</term><term>Tio2 layer</term><term>Tio2 overlayer</term><term>Titanium</term><term>Titanium implant surfaces</term><term>Titanium implants</term><term>Titanium layer</term><term>Titanium metal</term><term>Wide scan</term><term>Zinc salts</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Arys</term><term>Astm</term><term>Atomic percent</term><term>Atomic percent concentrations</term><term>Auger electron spectroscopic studies</term><term>Belgian fund</term><term>Binding energy</term><term>Biological tissues</term><term>Body tissues</term><term>Branemark</term><term>Bulk composition</term><term>Carbon material</term><term>Cell metabolism</term><term>Chemical composition</term><term>Complex geometry</term><term>Connective tissue</term><term>Corrosion resistance</term><term>Cpti</term><term>Cpti implants</term><term>Critical threshold</term><term>Crystallographic structure</term><term>Dent</term><term>Dental implants</term><term>Different brands</term><term>Different mechanisms</term><term>Electron microprobe</term><term>Electron microprobe analysis</term><term>Electron microprobe measurements</term><term>Element traces</term><term>Elemental composition</term><term>Favor osseointegration</term><term>Fifth world biomater</term><term>Foreign elements</term><term>Granular bodies</term><term>Hati</term><term>Hematoxylin eosin stain</term><term>High surface sensitivity</term><term>Histological</term><term>Histological slides</term><term>Implant</term><term>Implant failure</term><term>Implant surface</term><term>Implant threads</term><term>Integration failure</term><term>Iron particles</term><term>Jbma</term><term>John wiley sons</term><term>Large amount</term><term>Light microscopy</term><term>Medical research</term><term>Metal ions</term><term>Methods section</term><term>Microprobe</term><term>Nitride</term><term>Nitride species</term><term>Nitrogen content</term><term>Nobel pharma</term><term>Osseointegration</term><term>Osseointegration failure</term><term>Osteoid tissue</term><term>Other hand</term><term>Other implants</term><term>Overlayer</term><term>Oxide</term><term>Oxide dissolution</term><term>Oxide thickness</term><term>Oxidoreduction mechanism</term><term>Oxygen signal</term><term>Partial dissolution</term><term>Photoelectron</term><term>Photoelectron spectroscopy</term><term>Photoelectron spectroscopy results</term><term>Potential difference</term><term>Proprietary preparation procedures</term><term>Protective titanium dioxide overlayer</term><term>Pure titanium</term><term>Reactive metal</term><term>Reference implants</term><term>Sample surface</term><term>Sterile package</term><term>Surface analysis</term><term>Surface properties</term><term>Surface roughness</term><term>Surface science aspects</term><term>Surgical procedure</term><term>Thin tio2</term><term>Tio2</term><term>Tio2 layer</term><term>Tio2 overlayer</term><term>Titanium</term><term>Titanium implant surfaces</term><term>Titanium implants</term><term>Titanium layer</term><term>Titanium metal</term><term>Wide scan</term><term>Zinc salts</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Recherche médicale</term><term>Oxyde</term><term>Titane</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A multitechnique approach has been used to characterize the surface of nonosseointegrated titanium implants and the surrounding biological tissues. Five pure titanium dental implants were used as reference, and 25 removed implants were studied. Surface and in‐depth chemical compositions of the implants (from a total of 16 patients) were investigated by X‐ray photoelectron spectroscopy (XPS). Histological slides of the surrounding tissues were examined by light microscopy, XPS, and electron microprobe analysis. None of the failed implants presented the regular surface composition and depth profile of the TiO2 overlayer; foreign elements (Ca, Na, P, Si, Cl, Zn, Pb, and Al) were observed on some implants. Fibrosis, lymphocytic and plasmocytic infiltrates, and granulomatous lesions were detected in the surrounding tissues. XPS and electron microprobe analysis indicated the presence of Zn, Fe, Sn, and Ti in the tissues. As a possible scenario for implant failure, we propose and discuss a oxidoreduction mechanism, leading to a partial dissolution or the complete dissociation of the protective titanium dioxide overlayer and to ion diffusion through the surrounding tissues. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 43: 300–312, 1998</div></front></TEI><affiliations><list><country><li>Belgique</li></country><region><li>Région de Bruxelles-Capitale</li></region><settlement><li>Bruxelles</li></settlement><orgName><li>Université libre de Bruxelles</li></orgName></list><tree><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Arys, A" sort="Arys, A" uniqKey="Arys A" first="A." last="Arys">A. Arys</name></region><name sortKey="Dourov, N" sort="Dourov, N" uniqKey="Dourov N" first="N." last="Dourov">N. Dourov</name><name sortKey="Dourov, N" sort="Dourov, N" uniqKey="Dourov N" first="N." last="Dourov">N. Dourov</name><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name><name sortKey="Le, Q T" sort="Le, Q T" uniqKey="Le Q" first="Q. T." last="Le">Q. T. Le</name><name sortKey="Philippart, C" sort="Philippart, C" uniqKey="Philippart C" first="C." last="Philippart">C. Philippart</name><name sortKey="Pireaux, J J" sort="Pireaux, J J" uniqKey="Pireaux J" first="J. J." last="Pireaux">J. J. Pireaux</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/EdenteV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009A04 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009A04 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= EdenteV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:0048047ED90777A2254776581E303F523FC57BD1
|texte= Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X‐ray photoelectron spectroscopy approach
}}
| This area was generated with Dilib version V0.6.32. |  |